RUBRACA may cause side effects1

The most common side effects reported with RUBRACA include tiredness or weakness, muscle or joint pain, nausea, loss of appetite, diarrhea, constipation, vomiting, shortness of breath, changes in taste, swelling, abdominal pain, dizziness, weight loss, rash, headache, numbness or tingling in the hands or feet, sensitivity to light, and urinary tract infections.

RUBRACA can also cause a variety of abnormal results in laboratory tests, such as blood tests. Talk to your doctor about how to interpret laboratory abnormalities.

RUBRACA may cause serious side effects, such as bone marrow problems called myelodysplastic syndrome (MDS) or a type of blood cancer called acute myeloid leukemia (AML)

Some people who have received previous cancer treatment with chemotherapy or other medicines for their cancer have developed MDS or AML while taking RUBRACA.

  • Your doctor will perform weekly blood tests if you have low blood cell counts for a long time, and may stop treatment with RUBRACA until your blood cell counts improve
  • If you develop MDS or AML, your doctor will direct you to stop taking RUBRACA
RUBRACA may cause serious side effects

Tips for managing side effects

Always talk to your doctor about any side effects you may be experiencing. There may be things your doctor can do to help manage side effects, such as:

  • Reducing your dose or stopping treatment with RUBRACA for a period of time
  • Prescribing medications to help with certain side effects, such as nausea, vomiting, and diarrhea
RUBRACA may cause serious side effects

What you can do to help cope with tiredness or weakness

If you experience tiredness or weakness while taking RUBRACA, there are many simple things you can do daily that may help, such as:

  • Getting enough rest and sleep
  • Short walks or light exercise (if possible)
  • Eating healthy foods that give you energy
  • Stress-relieving activities
  • Not pushing yourself too hard
Your doctor will monitor you to assess how you are responding to treatment and may make changes to help manage any side effects1

Find helpful resources, including support groups you can join

EXPLORE NOW
REFERENCE: 1. RUBRACA (rucaparib). Prescribing Information. pharmaand GmbH. 2025.
Tap for safety information

IMPORTANT SAFETY INFORMATION

What is RUBRACA® (rucaparib) used for?

RUBRACA tablets are a prescription medicine used in adults for:

  • The treatment of castration-resistant prostate cancer (prostate cancer that no longer responds to medical or surgical treatment that lowers testosterone):
    • That has spread to other parts of the body (metastatic), and
    • Has a certain type of inherited (germline) or acquired (somatic) abnormal BRCA gene, and you have been treated with certain medicines for your cancer.
  • Your healthcare provider will perform a test to make sure RUBRACA is right for you.

It is not known if RUBRACA is safe and effective in children.

What Warnings should you know about RUBRACA?

RUBRACA tablets may cause serious side effects including: Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called Acute Myeloid Leukemia (AML). Some people who have cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with RUBRACA. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with RUBRACA. Symptoms may include weakness, weight loss, fever, frequent infections, blood in urine or stool, shortness of breath, feeling very tired, bruising or bleeding more easily. Symptoms of low blood cell counts are common during treatment with RUBRACA, but can be a sign of serious problems, including MDS or AML.

Before you take RUBRACA, tell your healthcare provider about all of your medical conditions, including if you are a male with a female partner who is pregnant or able to become pregnant, effective birth control should be used during treatment and for 3 months after the last dose of RUBRACA. Do not donate sperm during use and for 3 months after the last dose of RUBRACA.

What other important information should I know about RUBRACA?

Your healthcare provider will do blood tests before and every month during treatment with RUBRACA to monitor your blood cell counts. Weekly blood tests will be performed if you have low blood cell counts for a long time. Your healthcare provider may stop treatment with RUBRACA until your blood cell counts improve.

Avoid spending time in sunlight while on RUBRACA since your skin may become more sensitive to the sun and may sunburn more easily. You should wear a hat and clothes that cover your skin and use sunscreen to help protect against sunburn if you have to be in the sunlight.

What are the side effects of RUBRACA?

The most common side effects of RUBRACA in people with prostate cancer include: tiredness or weakness, muscle and joint pain, nausea, decrease in hemoglobin (anemia), decreased appetite, changes in liver and kidney function tests, constipation, diarrhea, vomiting, low blood cell counts, shortness of breath, swelling in your legs and feet, dizziness, decreased weight, stomach area (abdominal) pain, changes in how food tastes, rash, tingling sensation and numbness, cough, headache, urinary tract infection, bleeding, photosensitivity reaction.

These are not all the possible side effects of RUBRACA. Call your healthcare provider for medical advice about side effects.

What other medications might interact with RUBRACA?

RUBRACA can increase the amounts of other medications you may be taking, which can increase the risk of side effects. Tell your healthcare provider about all your medical conditions and all medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to pharma& at 1-800-506-8501.

  • This information is not comprehensive.
    • How to get more information:
      • Talk to your health care provider or pharmacist.
      • Visit www.rubracaprostate.com to obtain the FDA-approved product labeling.

Please see full Prescribing Information for RUBRACA.

FPO

YOU ARE NOW LEAVING RubracaProstate.com

Are you sure you want to leave?

Continue
Cancel and stay
Skip to content
Rubraca
Powered by  GDPR Cookie Compliance
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.